2ORV
human Thymidine Kinase 1 in complex with TP4A
Summary for 2ORV
Entry DOI | 10.2210/pdb2orv/pdb |
Related | 2ORW |
Descriptor | Thymidine kinase, ZINC ION, P1-(5'-ADENOSYL)P4-(5'-(2'-DEOXY-THYMIDYL))TETRAPHOSPHATE, ... (4 entities in total) |
Functional Keywords | tk-1 (thymidine kinase 1), tp4a (p1-(5'-adenosyl)p4-(5'-(2'deoxythymidil))tetraphosphate, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P04183 |
Total number of polymer chains | 2 |
Total formula weight | 52512.66 |
Authors | Segura-Pena, D.,Lutz, S.,Monnerjahn, C.,Konrad, M.,Lavie, A. (deposition date: 2007-02-04, release date: 2007-03-27, Last modification date: 2024-02-21) |
Primary citation | Segura-Pena, D.,Lutz, S.,Monnerjahn, C.,Konrad, M.,Lavie, A. Binding of ATP to TK1-like Enzymes Is Associated with a Conformational Change in the Quaternary Structure. J.Mol.Biol., 369:129-141, 2007 Cited by PubMed: 17407781DOI: 10.1016/j.jmb.2007.02.104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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