2O5J

Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the NTP substrate analog

Summary for 2O5J

• Entry DOI: 10.2210/pdb2o5j/pdb
• Descriptor: 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, 5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3', ... (11 entities in total)
• Functional Keywords: rna polymerase, elongation complex, template dna, non-template dna, rna transcript, ntp substrate, transferase-dna-rna hybrid complex, transferase/dna-rna hybrid
• Biological source: Thermus thermophilus; More
• Total number of polymer chains: 16
• Total formula weight: 790547.30

Authors

Vassylyev, D.G.,Vassylyeva, M.N. (deposition date: 2006-12-06, release date: 2007-07-03, Last modification date: 2023-08-30)

• Primary citation: Vassylyev, D.G.,Vassylyeva, M.N.,Zhang, J.,Palangat, M.,Artsimovitch, I.,Landick, R.; Structural basis for substrate loading in bacterial RNA polymerase.; Nature, 448:163-168, 2007; PubMed: 17581591; DOI: 10.1038/nature05931

Experimental method

X-RAY DIFFRACTION (3 Å)