2MLO

Human CCR2 Membrane-Proximal C-Terminal Region (PRO-C) in a Membrane bound form

Summary for 2MLO

• Entry DOI: 10.2210/pdb2mlo/pdb
• Related: 2MLQ
• NMR Information: BMRB: 19828
• Descriptor: MCP-1 receptor (1 entity in total)
• Functional Keywords: ccr2, pro-c, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Multi-pass membrane protein (By similarity): O95950
• Total number of polymer chains: 1
• Total formula weight: 2133.54

Authors

Esaki, K.,Yoshinaga, S.,Tsuji, T.,Toda, E.,Terashima, Y.,Saitoh, T.,Kohda, D.,Kohno, T.,Osawa, M.,Ueda, T.,Shimada, I.,Matsushima, K.,Terasawa, H. (deposition date: 2014-03-04, release date: 2014-10-08, Last modification date: 2023-06-14)

• Primary citation: Esaki, K.,Yoshinaga, S.,Tsuji, T.,Toda, E.,Terashima, Y.,Saitoh, T.,Kohda, D.,Kohno, T.,Osawa, M.,Ueda, T.,Shimada, I.,Matsushima, K.,Terasawa, H.; Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT.; Febs J., 281:5552-5566, 2014; PubMed: 25283965; DOI: 10.1111/febs.13096

Experimental method

SOLUTION NMR