2MD5

Structure of uninhibited ETV6 ETS domain

Summary for 2MD5

• Entry DOI: 10.2210/pdb2md5/pdb
• Related: 2LF7 2LF8 4MHG
• NMR Information: BMRB: 19474
• Descriptor: Transcription factor ETV6 (1 entity in total)
• Functional Keywords: protein, auto-inhibition, transcription
• Biological source: Mus musculus (mouse)
• Cellular location: Nucleus (By similarity): P97360
• Total number of polymer chains: 1
• Total formula weight: 12450.35

Authors

De, S.,Mcintosh, L.P.,Chan, A.C.,Coyne, H.J.,Okon, M.,Graves, B.J.,Murphy, M.E. (deposition date: 2013-08-29, release date: 2013-12-25, Last modification date: 2023-06-14)

• Primary citation: De, S.,Chan, A.C.,Coyne, H.J.,Bhachech, N.,Hermsdorf, U.,Okon, M.,Murphy, M.E.,Graves, B.J.,McIntosh, L.P.; Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6.; J.Mol.Biol., 426:1390-1406, 2014; PubMed: 24333486; DOI: 10.1016/j.jmb.2013.11.031

Experimental method

SOLUTION NMR