2KA4

NMR structure of the CBP-TAZ1/STAT2-TAD complex

Summary for 2KA4

• Entry DOI: 10.2210/pdb2ka4/pdb
• Related: 2KA6
• NMR Information: BMRB: 16014
• Descriptor: Crebbp protein, Signal transducer and activator of transcription 2, ZINC ION (3 entities in total)
• Functional Keywords: cbp/p300, stat2, taz1, transactivation domain, bromodomain, activator, alternative splicing, antiviral defense, cytoplasm, dna-binding, host-virus interaction, nucleus, phosphoprotein, polymorphism, sh2 domain, transcription, transcription regulation, transcription regulator
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 2
• Total formula weight: 17907.60

Authors

Wojciak, J.M.,Martinez-Yamout, M.A.,Dyson, H.J.,Wright, P.E. (deposition date: 2008-10-30, release date: 2009-04-21, Last modification date: 2021-10-20)

• Primary citation: Wojciak, J.M.,Martinez-Yamout, M.A.,Dyson, H.J.,Wright, P.E.; Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains; Embo J., 28:948-958, 2009; PubMed: 19214187; DOI: 10.1038/emboj.2009.30

Experimental method

SOLUTION NMR