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2JH5

Human Thrombin Hirugen Inhibitor complex

Summary for 2JH5
Entry DOI10.2210/pdb2jh5/pdb
Related2JH0 2JH6
DescriptorTHROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN, HIRUDIN IIIA, ... (7 entities in total)
Functional Keywordsglycoprotein, serine protease, kringle, zymogen, thrombin, protease, disease mutation, blood coagulation, gamma-carboxyglutamic acid, protease inhibitor, serine protease inhibitor, sulfation, acute phase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationSecreted, extracellular space: P00734 P00734
Secreted: P28507
Total number of polymer chains3
Total formula weight35751.18
Authors
Senger, S.,Chan, C.,Convery, M.A.,Hubbard, J.A.,Young, R.J.,Shah, G.P.,Watson, N.S. (deposition date: 2007-02-20, release date: 2007-05-08, Last modification date: 2017-06-28)
Primary citationSenger, S.,Chan, C.,Convery, M.A.,Hubbard, J.A.,Shah, G.P.,Watson, N.S.,Young, R.J.
Sulfonamide-Related Conformational Effects and Their Importance in Structure-Based Design.
Bioorg.Med.Chem.Lett., 17:2931-, 2007
Cited by
PubMed: 17336062
DOI: 10.1016/J.BMCL.2007.02.034
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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