2JCM

Crystal structure of Human Cytosolic 5'-Nucleotidase II in complex with beryllium trifluoride

Summary for 2JCM

Entry DOI	10.2210/pdb2jcm/pdb
Related	2J2C 2JC9
Descriptor	CYTOSOLIC PURINE 5'-NUCLEOTIDASE, UNKNOWN ATOM OR ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	cytosolic 5-prime nucleotidase ii, gmp-imp specific nucleotidase, cn-ii, nt5c2, hydrolase, cytosolic purine 5-prime nucleotidase, allosteric enzyme, high km 5-prime nucleotidase
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: P49902
Total number of polymer chains	1
Total formula weight	64370.36
Authors	Wallden, K.,Stenmark, P.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Edwards, A.,Ehn, M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg Schiavone, L.,Hogbom, M.,Karlberg, T.,Kotenyova, T.,Magnusdottir, A.,Nilsson-Ehle, P.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Sundstrom, M.,Uppenberg, J.,Thorsell, A.G.,Van Den Berg, S.,Loppnau, P.,Weigelt, J.,Welin, M.,Nordlund, P. (deposition date: 2006-12-27, release date: 2007-01-30, Last modification date: 2023-12-13)
Primary citation	Wallden, K.,Stenmark, P.,Nyman, T.,Flodin, S.,Graslund, S.,Loppnau, P.,Bianchi, V.,Nordlund, P. Crystal Structure of Human Cytosolic 5'- Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition J.Biol.Chem., 282:17828-, 2007 Cited by PubMed: 17405878 DOI: 10.1074/JBC.M700917200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation