2J67

The TIR domain of human Toll-Like Receptor 10 (TLR10)

Summary for 2J67

• Entry DOI: 10.2210/pdb2j67/pdb
• Descriptor: TOLL LIKE RECEPTOR 10 (2 entities in total)
• Functional Keywords: tir, il-1, toll, tlr10, membrane, receptor, inflammatory response, toll-like receptor 10, innate immunity, immune response, leucine-rich repeat, glycoprotein, transmembrane
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Membrane; Single-pass type I membrane protein (By similarity): Q9BXR5
• Total number of polymer chains: 2
• Total formula weight: 42578.57

Authors

Stenmark, P.,Ogg, D.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Edwards, A.,Ericsson, U.B.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg Schiavone, L.,Hogbom, M.,Johansson, I.,Karlberg, T.,Kotenyova, T.,Magnusdottir, A.,Nilsson, M.E.,Nilsson-Ehle, P.,Nyman, T.,Persson, C.,Sagemark, J.,Sundstrom, M.,Uppenberg, J.,Thorsell, A.G.,Van Den Berg, S.,Wallden, K.,Weigelt, J.,Welin, M.,Nordlund, P. (deposition date: 2006-09-26, release date: 2006-09-27, Last modification date: 2023-12-13)

• Primary citation: Nyman, T.,Stenmark, P.,Flodin, S.,Johansson, I.,Hammarstrom, M.,Nordlund, P.; The Crystal Structure of the Human Toll-Like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer.; J.Biol.Chem., 283:11861-, 2008; PubMed: 18332149; DOI: 10.1074/JBC.C800001200

Experimental method

X-RAY DIFFRACTION (2.2 Å)