2IGX
Achiral, Cheap and Potent Inhibitors of Plasmepsins II
Summary for 2IGX
Entry DOI | 10.2210/pdb2igx/pdb |
Related | 2BJU 2IGY |
Descriptor | Plasmepsin-2, 5-PENTYL-N-{[4'-(PIPERIDIN-1-YLCARBONYL)BIPHENYL-4-YL]METHYL}-N-[1-(PYRIDIN-2-YLMETHYL)PIPERIDIN-4-YL]PYRIDINE-2-CARBOXAMIDE (3 entities in total) |
Functional Keywords | achiral inhibitor, hydrolase |
Biological source | Plasmodium falciparum (malaria parasite P. falciparum) |
Cellular location | Vacuole: P46925 |
Total number of polymer chains | 1 |
Total formula weight | 37597.59 |
Authors | Prade, L. (deposition date: 2006-09-25, release date: 2006-11-28, Last modification date: 2017-10-18) |
Primary citation | Boss, C.,Corminboeuf, O.,Grisostomi, C.,Meyer, S.,Jones, A.F.,Prade, L.,Binkert, C.,Fischli, W.,Weller, T.,Bur, D. Achiral, Cheap, and Potent Inhibitors of Plasmepsins I, II, and IV. Chemmedchem, 1:1341-1345, 2006 Cited by PubMed: 17091526DOI: 10.1002/cmdc.200600223 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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