2IE4

Structure of the Protein Phosphatase 2A Core Enzyme Bound to okadaic acid

Summary for 2IE4

• Entry DOI: 10.2210/pdb2ie4/pdb
• Related: 2IE3
• Descriptor: Protein Phosphatase 2, regulatory subunit A (PR 65), alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, MANGANESE (II) ION, ... (5 entities in total)
• Functional Keywords: protein-protein complex, heat repeat, signaling protein, hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P67775
• Total number of polymer chains: 2
• Total formula weight: 101929.38

Authors

Xing, Y.,Xu, Y.,Chen, Y.,Jeffrey, P.D.,Chao, Y.,Shi, Y. (deposition date: 2006-09-17, release date: 2006-11-07, Last modification date: 2024-02-21)

• Primary citation: Xing, Y.,Xu, Y.,Chen, Y.,Jeffrey, P.D.,Chao, Y.,Lin, Z.,Li, Z.,Strack, S.,Stock, J.B.,Shi, Y.; Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins; Cell(Cambridge,Mass.), 127:341-353, 2006; PubMed: 17055435; DOI: 10.1016/j.cell.2006.09.025

Experimental method

X-RAY DIFFRACTION (2.6 Å)