2ICT

Crystal structure of the bacterial antitoxin HigA from Escherichia coli at pH 8.5. Northeast Structural Genomics TARGET ER390.

Summary for 2ICT

• Entry DOI: 10.2210/pdb2ict/pdb
• Related: 2ICP
• Descriptor: antitoxin higa (2 entities in total)
• Functional Keywords: helix-turn-helix, structural genomics, psi-2, protein structure initiative, northeast structural genomics consortium, nesg, dna binding protein
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 10647.54

Authors

Arbing, M.A.,Abashidze, M.,Hurley, J.M.,Zhao, L.,Janjua, H.,Cunningham, K.,Ma, L.C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Inouye, M.,Woychik, N.A.,Montelione, G.T.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2006-09-13, release date: 2006-09-26, Last modification date: 2017-10-18)

• Primary citation: Arbing, M.A.,Handelman, S.K.,Kuzin, A.P.,Verdon, G.,Wang, C.,Su, M.,Rothenbacher, F.P.,Abashidze, M.,Liu, M.,Hurley, J.M.,Xiao, R.,Acton, T.,Inouye, M.,Montelione, G.T.,Woychik, N.A.,Hunt, J.F.; Crystal Structures of Phd-Doc, HigA, and YeeU Establish Multiple Evolutionary Links between Microbial Growth-Regulating Toxin-Antitoxin Systems.; Structure, 18:996-1010, 2010; PubMed: 20696400; DOI: 10.1016/j.str.2010.04.018

Experimental method

X-RAY DIFFRACTION (1.63 Å)