2I75

Crystal Structure of Human Protein Tyrosine Phosphatase N4 (PTPN4)

Summary for 2I75

Entry DOI	10.2210/pdb2i75/pdb
Related	2B49
Descriptor	Tyrosine-protein phosphatase non-receptor type 4, SULFATE ION (3 entities in total)
Functional Keywords	ptpn4, ptp, tyrosine phosphatase, meg-1, structural genomics, structural genomics consortium, sgc, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : P29074
Total number of polymer chains	1
Total formula weight	36873.77
Authors	Ugochukwu, E.,Barr, A.,Savitsky, P.,Burgess, N.,Das, S.,Turnbull, A.,von Delft, F.,Sundstrom, M.,Edwards, A.,Arrowsmith, C.,Weigelt, J.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2006-08-30, release date: 2006-10-17, Last modification date: 2023-08-30)
Primary citation	Barr, A.J.,Ugochukwu, E.,Lee, W.H.,King, O.N.,Filippakopoulos, P.,Alfano, I.,Savitsky, P.,Burgess-Brown, N.A.,Muller, S.,Knapp, S. Large-scale structural analysis of the classical human protein tyrosine phosphatome. Cell(Cambridge,Mass.), 136:352-363, 2009 Cited by PubMed: 19167335 DOI: 10.1016/j.cell.2008.11.038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation