7AQB

Crystal structure of human mitogen activated protein kinase 6 (MAPK6)

Replaces:  2I6L

Summary for 7AQB

• Entry DOI: 10.2210/pdb7aqb/pdb
• Descriptor: Mitogen-activated protein kinase 6, MAGNESIUM ION, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: mapk6, erk3, kinase, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 72647.87

Authors

Filippakopoulos, P.,Schroeder, M.,Chaikuad, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-10-20, release date: 2020-11-11, Last modification date: 2024-01-31)

• Primary citation: Schroder, M.,Filippakopoulos, P.,Schwalm, M.P.,Ferrer, C.A.,Drewry, D.H.,Knapp, S.,Chaikuad, A.; Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3.; Int J Mol Sci, 21:-, 2020; PubMed: 33114754; DOI: 10.3390/ijms21217953

Experimental method

X-RAY DIFFRACTION (2.25 Å)