2I61

Depressant anti-insect neurotoxin, LqhIT2 from Leiurus quinquestriatus hebraeus

Summary for 2I61

• Entry DOI: 10.2210/pdb2i61/pdb
• Descriptor: Insect toxin 2, LITHIUM ION, SULFATE ION, ... (7 entities in total)
• Functional Keywords: scorpion toxin, depressant, anti-insect, sodium channel modifer, toxin
• Biological source: Leiurus quinquestriatus hebraeus
• Cellular location: Secreted: Q26292
• Total number of polymer chains: 1
• Total formula weight: 7312.96

Authors

Frolow, F.,Gurevitz, M.,Karbat, I.,Turkov, M.,Gordon, D. (deposition date: 2006-08-27, release date: 2006-12-26, Last modification date: 2023-08-30)

• Primary citation: Karbat, I.,Turkov, M.,Cohen, L.,Kahn, R.,Gordon, D.,Gurevitz, M.,Frolow, F.; X-ray Structure and Mutagenesis of the Scorpion Depressant Toxin LqhIT2 Reveals Key Determinants Crucial for Activity and Anti-Insect Selectivity.; J.Mol.Biol., 366:586-601, 2007; PubMed: 17166514; DOI: 10.1016/j.jmb.2006.10.085

Experimental method

X-RAY DIFFRACTION (1.2 Å)