2I1Y

Crystal structure of the phosphatase domain of human PTP IA-2

2I1Y の概要

分子名称Receptor-type tyrosine-protein phosphatase, GLYCEROL (3 entities in total)
機能のキーワードreceptor-type protein tyrosine phosphatase precursor, phosphatase, structural genomics, psi, protein structure initiative, new york sgx research center for structural genomics, nysgxrc, hydrolase
由来する生物種Homo sapiens (human)
細胞内の位置Membrane; Single-pass type I membrane protein Q16849
ポリマー鎖数2
分子量合計68770.23
構造登録者
主引用文献
Almo, S.C.,Bonanno, J.B.,Sauder, J.M.,Emtage, S.,Dilorenzo, T.P.,Malashkevich, V.,Wasserman, S.R.,Swaminathan, S.,Eswaramoorthy, S.,Agarwal, R.,Kumaran, D.,Madegowda, M.,Ragumani, S.,Patskovsky, Y.,Alvarado, J.,Ramagopal, U.A.,Faber-Barata, J.,Chance, M.R.,Sali, A.,Fiser, A.,Zhang, Z.Y.,Lawrence, D.S.,Burley, S.K.
Structural genomics of protein phosphatases
J.STRUCT.FUNCT.GENOM., 8:121-140, 2007
PubMed: 18058037 (主引用文献が同じPDBエントリー)
DOI: 10.1007/s10969-007-9036-1
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.23 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.26330.7%6.6%3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード