2I1Y

Crystal structure of the phosphatase domain of human PTP IA-2

Summary for 2I1Y

• Entry DOI: 10.2210/pdb2i1y/pdb
• Descriptor: Receptor-type tyrosine-protein phosphatase, GLYCEROL (3 entities in total)
• Functional Keywords: receptor-type protein tyrosine phosphatase precursor, phosphatase, structural genomics, psi, protein structure initiative, new york sgx research center for structural genomics, nysgxrc, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 68770.23

Authors

Faber-Barata, J.,Patskovsky, Y.,Alvarado, J.,Smith, D.,Koss, J.,Wasserman, S.R.,Ozyurt, S.,Atwell, S.,Powell, A.,Kearins, M.C.,Maletic, M.,Rooney, I.,Bain, K.T.,Freeman, M.,Russell, J.C.,Thompson, D.A.,Burley, S.K.,Almo, S.C.,New York SGX Research Center for Structural Genomics (NYSGXRC) (deposition date: 2006-08-15, release date: 2006-08-29, Last modification date: 2023-08-30)

• Primary citation: Almo, S.C.,Bonanno, J.B.,Sauder, J.M.,Emtage, S.,Dilorenzo, T.P.,Malashkevich, V.,Wasserman, S.R.,Swaminathan, S.,Eswaramoorthy, S.,Agarwal, R.,Kumaran, D.,Madegowda, M.,Ragumani, S.,Patskovsky, Y.,Alvarado, J.,Ramagopal, U.A.,Faber-Barata, J.,Chance, M.R.,Sali, A.,Fiser, A.,Zhang, Z.Y.,Lawrence, D.S.,Burley, S.K.; Structural genomics of protein phosphatases; J.STRUCT.FUNCT.GENOM., 8:121-140, 2007; PubMed: 18058037; DOI: 10.1007/s10969-007-9036-1

Experimental method

X-RAY DIFFRACTION (2.23 Å)