2HYI

Structure of the human exon junction complex with a trapped DEAD-box helicase bound to RNA

Summary for 2HYI

• Entry DOI: 10.2210/pdb2hyi/pdb
• Related: 1p27 2db3 2hxy
• Descriptor: 5'-R(*UP*UP*UP*UP*UP*U)-3', Protein mago nashi homolog, RNA-binding protein 8A, ... (8 entities in total)
• Functional Keywords: exon junction, splicing, mrna processing, translation, dead-box atpase, nonsense mediated decay, hydrolase-rna binding protein-rna complex, hydrolase/rna binding protein/rna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P61326 Q9Y5S9 P38919; Cytoplasm, perinuclear region: O15234
• Total number of polymer chains: 10
• Total formula weight: 172982.64

Authors

Andersen, C.B.F.,Le Hir, H.,Andersen, G.R. (deposition date: 2006-08-06, release date: 2006-08-15, Last modification date: 2024-02-21)

• Primary citation: Andersen, C.B.F.,Ballut, L.,Johansen, J.S.,Chamieh, H.,Nielsen, K.H.,Oliveira, C.L.,Pedersen, J.S.,Seraphin, B.,Le Hir, H.,Andersen, G.R.; Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.; Science, 313:1968-1972, 2006; PubMed: 16931718; DOI: 10.1126/science.1131981

Experimental method

X-RAY DIFFRACTION (2.3 Å)