2HTW

N4 neuraminidase in complex with DANA

Summary for 2HTW

Related2HT5 2HT7 2HT8 2HTU 2HTQ 2HTV 2HTR 2HTY 2HU0 2HU4
DescriptorNeuraminidase, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID (2 entities in total)
Functional Keywordsn4, neuraminidase, dana, hydrolase
Biological sourceInfluenza A virus
Total number of polymer chains1
Total molecular weight43224.25
Authors
Russell, R.J.,Haire, L.F.,Stevens, D.J.,Collins, P.J.,Lin, Y.P.,Blackburn, G.M.,Hay, A.J.,Gamblin, S.J.,Skehel, J.J. (deposition date: 2006-07-26, release date: 2006-09-05, Last modification date: 2011-07-13)
Primary citation
Russell, R.J.,Haire, L.F.,Stevens, D.J.,Collins, P.J.,Lin, Y.P.,Blackburn, G.M.,Hay, A.J.,Gamblin, S.J.,Skehel, J.J.
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443:45-49, 2006
PubMed: 16915235 (PDB entries with the same primary citation)
DOI: 10.1038/nature05114
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.203404.1%7.3%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution