2HQ5

Crystal structure of multidrug binding protein QacR from Staphylococcus aureus cocrystallized with compound DB359

Summary for 2HQ5

Entry DOI	10.2210/pdb2hq5/pdb
Related	1JT6 1RKW 1RPW 2DTZ
Descriptor	HTH-type transcriptional regulator qacR, SULFATE ION (3 entities in total)
Functional Keywords	multidrug recognition, db359, qacr, multidrug binding protein, transcription
Biological source	Staphylococcus aureus
Total number of polymer chains	4
Total formula weight	93276.97
Authors	Brooks, B.E.,Brennan, R.G. (deposition date: 2006-07-18, release date: 2007-07-17, Last modification date: 2023-10-25)
Primary citation	Brooks, B.E.,Piro, K.M.,Brennan, R.G. Multidrug-Binding Transcription Factor QacR Binds the Bivalent Aromatic Diamidines DB75 and DB359 in Multiple Positions J.Am.Chem.Soc., 129:8389-8395, 2007 Cited by PubMed: 17567017 DOI: 10.1021/ja072576v PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation