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2H8R

Hepatocyte Nuclear Factor 1b bound to DNA: MODY5 Gene Product

Summary for 2H8R
Entry DOI10.2210/pdb2h8r/pdb
Descriptor5'-D(*CP*TP*TP*GP*GP*TP*TP*AP*AP*TP*AP*AP*TP*TP*CP*AP*CP*CP*AP*G)-3', 5'-D(*GP*CP*TP*GP*GP*TP*GP*AP*AP*TP*TP*AP*TP*TP*AP*AP*CP*CP*AP*A)-3', Hepatocyte nuclear factor 1-beta, ... (4 entities in total)
Functional Keywordstrasncription factor, pou, homeo, protein-dna, human disease, transcription activator-dna complex, transcription activator/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus: P35680
Total number of polymer chains4
Total formula weight63688.69
Authors
Lu, P.,Rha, G.B.,Chi, Y.I. (deposition date: 2006-06-07, release date: 2007-06-19, Last modification date: 2023-08-30)
Primary citationLu, P.,Rha, G.B.,Chi, Y.I.
Structural basis of disease-causing mutations in hepatocyte nuclear factor 1beta.
Biochemistry, 46:12071-12080, 2007
Cited by
PubMed: 17924661
DOI: 10.1021/bi7010527
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.2 Å)
Structure validation

217705

건을2024-03-27부터공개중

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