2GZV

The cystal structure of the PDZ domain of human PICK1

Summary for 2GZV

Entry DOI	10.2210/pdb2gzv/pdb
Descriptor	PRKCA-binding protein (2 entities in total)
Functional Keywords	protein kinase c, pdz domain, structural genomics, structural genomics consortium, sgc, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, perinuclear region: Q9NRD5
Total number of polymer chains	1
Total formula weight	12427.16
Authors	Debreczeni, J.E.,Elkins, J.M.,Yang, X.,Berridge, G.,Bray, J.,Colebrook, S.,Smee, C.,Savitsky, P.,Gileadi, O.,Turnbull, A.,von Delft, F.,Doyle, D.A.,Sundstrom, M.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Structural Genomics Consortium (SGC) (deposition date: 2006-05-12, release date: 2006-07-18, Last modification date: 2023-08-30)
Primary citation	Elkins, J.M.,Papagrigoriou, E.,Berridge, G.,Yang, X.,Phillips, C.,Gileadi, C.,Savitsky, P.,Doyle, D.A. Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions. Protein Sci., 16:683-694, 2007 Cited by PubMed: 17384233 DOI: 10.1110/ps.062657507 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.12 Å)

Structure validation