2GJT

Crystal structure of the human receptor phosphatase PTPRO

Summary for 2GJT

• Entry DOI: 10.2210/pdb2gjt/pdb
• Related: 2AHS
• Descriptor: Receptor-type tyrosine-protein phosphatase PTPRO, CHLORIDE ION (3 entities in total)
• Functional Keywords: tyrosine phosphatase, ptpro, glepp1, ptpu2, structural genomics, structural genomics consortium, sgc, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Single-pass type I membrane protein: Q16827
• Total number of polymer chains: 2
• Total formula weight: 69481.48

Authors

Barr, A.,Ugochukwu, E.,Eswaran, J.,Das, S.,Niesen, F.,Savitsky, P.,Turnbull, A.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Weigelt, J.,von Delft, F.,Papagrigoriou, E.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2006-03-31, release date: 2006-05-02, Last modification date: 2023-08-30)

• Primary citation: Barr, A.J.,Ugochukwu, E.,Lee, W.H.,King, O.N.,Filippakopoulos, P.,Alfano, I.,Savitsky, P.,Burgess-Brown, N.A.,Muller, S.,Knapp, S.; Large-scale structural analysis of the classical human protein tyrosine phosphatome.; Cell(Cambridge,Mass.), 136:352-363, 2009; PubMed: 19167335; DOI: 10.1016/j.cell.2008.11.038

Experimental method

X-RAY DIFFRACTION (2.15 Å)