2GEV

Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with a coenzyme A derivative, Form-II (LT)

Summary for 2GEV

Entry DOI	10.2210/pdb2gev/pdb
Related	2ges 2get 2geu
Descriptor	Pantothenate kinase, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-3-HYDROXY-4-{[3-({2-[(2-HYDROXYETHYL)DITHIO]ETHYL}AMINO)-3-OXOPROPYL]AMINO}-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
Functional Keywords	homodimer, coa biosynthesis, nucleotide binding, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	37299.32
Authors	Das, S.,Kumar, P.,Bhor, V.,Surolia, A.,Vijayan, M. (deposition date: 2006-03-20, release date: 2006-06-06, Last modification date: 2023-10-25)
Primary citation	Das, S.,Kumar, P.,Bhor, V.,Surolia, A.,Vijayan, M. Invariance and variability in bacterial PanK: a study based on the crystal structure of Mycobacterium tuberculosis PanK. Acta Crystallogr.,Sect.D, 62:628-638, 2006 Cited by PubMed: 16699190 DOI: 10.1107/S0907444906012728 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation