2FJX

RT29 bound to D(CTTGAATGCATTCAAG) in complex with MMLV RT catalytic fragment

Summary for 2FJX

• Entry DOI: 10.2210/pdb2fjx/pdb
• Related: 2FJV 2FJW
• Descriptor: 5'-D(*CP*TP*TP*GP*AP*AP*TP*G)-3', 5'-D(P*CP*AP*TP*TP*CP*AP*AP*G)-3', Reverse transcriptase, ... (5 entities in total)
• Functional Keywords: mmlv rt, protein-dna complex, water-mediated interaction, dna-drug complex, rt29, transferase-dna complex, transferase/dna
• Biological source: Moloney murine leukemia virus
• Cellular location: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor (Potential). Matrix protein p15: Virion (Potential). Capsid protein p30: Virion (Potential). Nucleocapsid protein p10: Virion (Potential): P03355
• Total number of polymer chains: 3
• Total formula weight: 34156.94

Authors

Goodwin, K.D.,Georgiadis, M.M. (deposition date: 2006-01-03, release date: 2006-06-27, Last modification date: 2024-02-14)

• Primary citation: Goodwin, K.D.,Lewis, M.A.,Tanious, F.A.,Tidwell, R.R.,Wilson, W.D.,Georgiadis, M.M.,Long, E.C.; A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine.; J.Am.Chem.Soc., 128:7846-7854, 2006; PubMed: 16771498; DOI: 10.1021/ja0600936

Experimental method

X-RAY DIFFRACTION (1.8 Å)