2FIV

Crystal structure of feline immunodeficiency virus protease complexed with a substrate

2FIV の概要

• エントリーDOI: 10.2210/pdb2fiv/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000427
• 分子名称: FELINE IMMUNODEFICIENCY VIRUS PROTEASE, ACE-ALN-VAL-STA-GLU-ALN-NH2, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: hydrolase-hydrolase inhibitor complex, acid proteinase-substrate, aspartic protease, retroviral protease, hydrolase/hydrolase inhibitor
• 由来する生物種: Feline immunodeficiency virus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 28332.68

構造登録者

Schalk-Hihi, C.,Lubkowski, J.,Zdanov, A.,Wlodawer, A.,Gustchina, A. (登録日: 1997-07-21, 公開日: 1997-11-12, 最終更新日: 2023-08-09)

• 主引用文献: Laco, G.S.,Schalk-Hihi, C.,Lubkowski, J.,Morris, G.,Zdanov, A.,Olson, A.,Elder, J.H.,Wlodawer, A.,Gustchina, A.; Crystal structures of the inactive D30N mutant of feline immunodeficiency virus protease complexed with a substrate and an inhibitor.; Biochemistry, 36:10696-10708, 1997; PubMed: 9271500; DOI: 10.1021/bi9707436

実験手法

X-RAY DIFFRACTION (2 Å)