2BZN

Crystal structure of human guanosine monophosphate reductase 2 GMPR2 in complex with IMP

Summary for 2BZN

Entry DOI	10.2210/pdb2bzn/pdb
Related	2A7R 2C6Q
Descriptor	GMP REDUCTASE 2, INOSINIC ACID (3 entities in total)
Functional Keywords	tim barrel, oxidoreductase
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	8
Total formula weight	308045.99
Authors	Stenmark, P.,Kursula, P.,Arrowsmith, C.,Berglund, H.,Edwards, A.,Ehn, M.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Kotenyova, T.,Nilsson-Ehle, P.,Nordlund, P.,Ogg, D.,Persson, C.,Sagemark, J.,Schuler, H.,Sundstrom, M.,Thorsell, A.,Weigelt, J. (deposition date: 2005-08-19, release date: 2005-09-02, Last modification date: 2023-12-13)
Primary citation	Patton, G.C.,Stenmark, P.,Gollapalli, D.R.,Sevastik, R.,Kursula, P.,Flodin, S.,Schuler, H.,Swales, C.T.,Eklund, H.,Himo, F.,Nordlund, P.,Hedstrom, L. Cofactor Mobility Determines Reaction Outcome in the Impdh and Gmpr (Beta-Alpha)(8) Barrel Enzymes. Nat.Chem.Biol., 7:950-, 2011 Cited by PubMed: 22037469 DOI: 10.1038/NCHEMBIO.693 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation