2ARV

Structure of human Activin A

Summary for 2ARV

• Entry DOI: 10.2210/pdb2arv/pdb
• Related: 2ARP
• Descriptor: Inhibin beta A chain, SULFATE ION, GLYCEROL, ... (5 entities in total)
• Functional Keywords: homodimer, cystine knot, disulfide linked, hormone-growth factor complex, hormone/growth factor
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P08476
• Total number of polymer chains: 2
• Total formula weight: 26896.57

Authors

Harrington, A.E.,Morris-Triggs, S.A.,Ruotolo, B.T.,Robinson, C.V.,Ohnuma, S.,Hyvonen, M. (deposition date: 2005-08-22, release date: 2006-03-07, Last modification date: 2023-08-23)

• Primary citation: Harrington, A.E.,Morris-Triggs, S.A.,Ruotolo, B.T.,Robinson, C.V.,Ohnuma, S.,Hyvonen, M.; Structural basis for the inhibition of activin signalling by follistatin; Embo J., 25:1035-1045, 2006; PubMed: 16482217; DOI: 10.1038/sj.emboj.7601000

Experimental method

X-RAY DIFFRACTION (2 Å)