2AO7

Adam10 Disintegrin and cysteine- rich domain

Summary for 2AO7

Entry DOI	10.2210/pdb2ao7/pdb
Descriptor	ADAM 10, SULFATE ION (2 entities in total)
Functional Keywords	extracellular, protease, disintegrin, hydrolase
Biological source	Bos taurus (cattle)
Cellular location	Golgi apparatus membrane; Single-pass type I membrane protein: Q10741
Total number of polymer chains	1
Total formula weight	21062.79
Authors	Janes, P.W.,Saha, N.,Barton, W.A.,Kolev, M.V.,Wimmer-Kleikamp, S.H.,Nievergall, E.,Blobel, C.P.,Himanen, J.-P.,Lackmann, M.,Nikolov, D.B. (deposition date: 2005-08-12, release date: 2006-08-08, Last modification date: 2011-07-13)
Primary citation	Janes, P.W.,Saha, N.,Barton, W.A.,Kolev, M.V.,Wimmer-Kleikamp, S.H.,Nievergall, E.,Blobel, C.P.,Himanen, J.-P.,Lackmann, M.,Nikolov, D.B. Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans. Cell(Cambridge,Mass.), 123:291-304, 2005 Cited by PubMed: 16239135 DOI: 10.1016/j.cell.2005.08.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation