2ZA0

Crystal structure of mouse glyoxalase I complexed with methyl-gerfelin

Summary for 2ZA0

Entry DOI	10.2210/pdb2za0/pdb
Related	1FRO 1QIN 1QIP
Descriptor	Glyoxalase I, ZINC ION, methyl 4-(2,3-dihydroxy-5-methylphenoxy)-2-hydroxy-6-methylbenzoate, ... (4 entities in total)
Functional Keywords	lyase, lactoylglutathione lyase, glyoxalase i, methyl-gerfelin
Biological source	Mus musculus (Mouse)
Total number of polymer chains	2
Total formula weight	42410.58
Authors	Okumura, H.,Kawatani, M.,Osada, H. (deposition date: 2007-09-26, release date: 2008-08-12, Last modification date: 2023-11-01)
Primary citation	Kawatani, M.,Okumura, H.,Honda, K.,Kanoh, N.,Muroi, M.,Dohmae, N.,Takami, M.,Kitagawa, M.,Futamura, Y.,Imoto, M.,Osada, H. The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I Proc.Natl.Acad.Sci.Usa, 105:11691-11696, 2008 Cited by PubMed: 18695250 DOI: 10.1073/pnas.0712239105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation