Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2WFG

Structure of the Candida albicans cytosolic leucyl-tRNA synthetase editing domain bound to a benzoxaborole-AMP adduct

Summary for 2WFG
Entry DOI10.2210/pdb2wfg/pdb
Related2WFE
DescriptorCYTOSOLIC LEUCYL-TRNA SYNTHETASE, [(1S,3S,5R,6R,8R)-6-(6-AMINOPURIN-9-YL)-4'-ETHYLAMINO-3'-FLUORO-SPIRO[2,4,7-TRIOXA-3-BORANUIDABICYCLO[3.3.0]OCTANE-3,7'-8-OXA-7-BORANUIDABICYCLO[4.3.0]NONA-1,3,5-TRIENE]-8-YL]METHYL DIHYDROGEN PHOSPHATE (3 entities in total)
Functional Keywordsligase, leucyl-trna synthetase, editing domain, candida albicans, hydrolysis of mis-charged trnas, benzoxaborole, anti-fungal
Biological sourceCANDIDA ALBICANS
Total number of polymer chains1
Total formula weight30019.81
Authors
Seiradake, E.,Mao, W.,Hernandez, V.,Baker, S.J.,Plattner, J.J.,Alley, M.R.K.,Cusack, S. (deposition date: 2009-04-05, release date: 2009-05-19, Last modification date: 2011-07-13)
Primary citationSeiradake, E.,Mao, W.,Hernandez, V.,Baker, S.J.,Plattner, J.J.,Alley, M.R.K.,Cusack, S.
Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles.
J.Mol.Biol., 390:196-, 2009
Cited by
PubMed: 19426743
DOI: 10.1016/J.JMB.2009.04.073
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

217705

건을2024-03-27부터공개중

PDB statisticsPDBj update infoContact PDBjnumon