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2VV0

hPPARgamma Ligand binding domain in complex with DHA

Summary for 2VV0
Entry DOI10.2210/pdb2vv0/pdb
Related1FM6 1FM9 1I7I 1K74 1KNU 1NYX 1PRG 1RDT 1WM0 1ZGY 2F4B 2FVJ 2G0G 2G0H 2PRG 2VSR 2VST 2VV1 2VV2 2VV3 2VV4 3PRG 4PRG
DescriptorPEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA, DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID (3 entities in total)
Functional Keywordsnuclear receptor, transcription regulation, alternative splicing, ligand binding domain, diabetes mellitus, zinc-finger, dna-binding, polymorphism, transcription, zinc, obesity, nucleus, receptor, activator, oxidised fatty acid, transcription factor, metal-binding, phosphoprotein, disease mutation
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains2
Total formula weight63556.02
Authors
Itoh, T.,Fairall, L.,Schwabe, J.W.R. (deposition date: 2008-06-02, release date: 2008-08-19, Last modification date: 2023-12-13)
Primary citationItoh, T.,Fairall, L.,Amin, K.,Inaba, Y.,Szanto, A.,Balint, B.L.,Nagy, L.,Yamamoto, K.,Schwabe, J.W.R.
Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15:924-, 2008
Cited by
PubMed: 19172745
DOI: 10.1038/NSMB.1474
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.55 Å)
Structure validation

217705

数据于2024-03-27公开中

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