2RNY

Complex Structures of CBP Bromodomain with H4 ack20 Peptide

Summary for 2RNY

Entry DOI	10.2210/pdb2rny/pdb
Descriptor	CREB-binding protein, Histone H4 (2 entities in total)
Functional Keywords	bromodomain, histone, creb, cbp, p53, acetylation, activator, chromosomal rearrangement, disease mutation, host-virus interaction, metal-binding, methylation, nucleus, phosphoprotein, transcription, transcription regulation, transferase, zinc, zinc-finger, chromosomal protein, dna-binding, nucleosome core, transferase-nuclear protein complex, transferase/nuclear protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: Q92793 Nucleus: P62805
Total number of polymer chains	2
Total formula weight	16213.63
Authors	Zeng, L.,Zhang, Q.,Gerona-Navarro, G.,Zhou, M.M. (deposition date: 2008-02-03, release date: 2008-05-06, Last modification date: 2023-11-15)
Primary citation	Zeng, L.,Zhang, Q.,Gerona-Navarro, G.,Moshkina, N.,Zhou, M.M. Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300 Structure, 16:643-652, 2008 Cited by PubMed: 18400184 DOI: 10.1016/j.str.2008.01.010 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation