2RNX

The Structural Basis for Site-Specific Lysine-Acetylated Histone Recognition by the Bromodomains of the HUman Transcriptional Co-Activators PCAF and CBP

2RNX の概要

• エントリーDOI: 10.2210/pdb2rnx/pdb
• 関連するPDBエントリー: 2RNW
• 分子名称: Histone acetyltransferase PCAF, Histone H3 (2 entities in total)
• 機能のキーワード: bromodomain, histone, acetyltransferase, acyltransferase, cell cycle, host-virus interaction, nucleus, polymorphism, transcription, transcription regulation, acetylation, chromosomal protein, dna damage, dna repair, dna-binding, methylation, nucleosome core, phosphoprotein, transferase-nuclear protein complex, transferase/nuclear protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus (By similarity): Q92831; Nucleus: P61830
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 15559.00

構造登録者

Zeng, L.,Zhang, Q.,Gerona-Navarro, G.,Zhou, M.M. (登録日: 2008-02-03, 公開日: 2008-05-06, 最終更新日: 2023-11-15)

• 主引用文献: Zeng, L.,Zhang, Q.,Gerona-Navarro, G.,Moshkina, N.,Zhou, M.M.; Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300; Structure, 16:643-652, 2008; PubMed: 18400184; DOI: 10.1016/j.str.2008.01.010

実験手法

SOLUTION NMR