2Q1Q

Carbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: kinetic and X-Ray crystallographic studies

Summary for 2Q1Q

Entry DOI	10.2210/pdb2q1q/pdb
Descriptor	Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (5 entities in total)
Functional Keywords	antiepileptic, carbonic anhydrase, inhibitors, lyase
Cellular location	Cytoplasm : P00918
Total number of polymer chains	1
Total formula weight	29845.42
Authors	Temperini, C.,Innocenti, A.,Mastrolorenzo, A.,Scozzafava, A.,Supuran, C.T. (deposition date: 2007-05-25, release date: 2007-09-11, Last modification date: 2024-02-21)
Primary citation	Temperini, C.,Innocenti, A.,Mastrolorenzo, A.,Scozzafava, A.,Supuran, C.T. Carbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: Kinetic and X-ray crystallographic studies. Bioorg.Med.Chem.Lett., 17:4866-4872, 2007 Cited by PubMed: 17588751 DOI: 10.1016/j.bmcl.2007.06.044 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation