2OKJ

The X-ray crystal structure of the 67kDa isoform of Glutamic Acid Decarboxylase (GAD67)

2OKJ の概要

• エントリーDOI: 10.2210/pdb2okj/pdb
• 関連するPDBエントリー: 2OKK
• 分子名称: Glutamate decarboxylase 1, GAMMA-AMINO-BUTANOIC ACID, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID, ... (4 entities in total)
• 機能のキーワード: plp-dependent decarboxylase, lyase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 115307.78

構造登録者

Buckle, A.M.,Fenalti, G.,Law, R.H.P.,Whisstock, J.C. (登録日: 2007-01-17, 公開日: 2007-03-27, 最終更新日: 2023-11-15)

• 主引用文献: Fenalti, G.,Law, R.H.P.,Buckle, A.M.,Langendorf, C.,Tuck, K.,Rosado, C.J.,Faux, N.G.,Mahmood, K.,Hampe, C.S.,Banga, J.P.,Wilce, M.,Schmidberger, J.,Rossjohn, J.,El-Kabbani, O.,Pike, R.N.,Smith, A.I.,Mackay, I.R.,Rowley, M.J.,Whisstock, J.C.; GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.; Nat.Struct.Mol.Biol., 14:280-286, 2007; PubMed: 17384644; DOI: 10.1038/nsmb1228

実験手法

X-RAY DIFFRACTION (2.3 Å)