2O3Z

X-ray crystal structure of LpxC complexed with 3-heptyloxybenzoate

Summary for 2O3Z

Entry DOI	10.2210/pdb2o3z/pdb
Related	1P42
Descriptor	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, SULFATE ION, ZINC ION, ... (6 entities in total)
Functional Keywords	lipid a biosynthesis, lipid synthesis, lpxc, 3-heptyloxybenzoate, hydrolase
Biological source	Aquifex aeolicus
Total number of polymer chains	2
Total formula weight	63006.26
Authors	Gennadios, H.A.,Whittington, D.A.,Christianson, D.W. (deposition date: 2006-12-02, release date: 2007-02-27, Last modification date: 2023-08-30)
Primary citation	Shin, H.,Gennadios, H.A.,Whittington, D.A.,Christianson, D.W. Amphipathic benzoic acid derivatives: synthesis and binding in the hydrophobic tunnel of the zinc deacetylase LpxC. Bioorg.Med.Chem., 15:2617-2623, 2007 Cited by PubMed: 17296300 DOI: 10.1016/j.bmc.2007.01.044 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation