2K78

Solution Structure of the IsdC NEAT domain bound to Zinc Protoporphyrin

Summary for 2K78

Entry DOI	10.2210/pdb2k78/pdb
NMR Information	BMRB: 15913
Descriptor	Iron-regulated surface determinant protein C, PROTOPORPHYRIN IX CONTAINING ZN (2 entities in total)
Functional Keywords	neat domain, nmr complex, heme, isd, isdc, cell wall, iron, metal-binding, peptidoglycan-anchor, secreted, transport protein, heme-binding protein
Biological source	Staphylococcus aureus (strain MW2)
Cellular location	Secreted, cell wall; Peptidoglycan-anchor (By similarity): Q7A151
Total number of polymer chains	1
Total formula weight	17251.47
Authors	Villareal, V.A.,Pilpa, R.M.,Robson, S.A.,Fadeev, E.A.,Clubb, R.T. (deposition date: 2008-08-06, release date: 2008-08-19, Last modification date: 2022-03-16)
Primary citation	Villareal, V.A.,Pilpa, R.M.,Robson, S.A.,Fadeev, E.A.,Clubb, R.T. The IsdC Protein from Staphylococcus aureus Uses a Flexible Binding Pocket to Capture Heme. J.Biol.Chem., 283:31591-31600, 2008 Cited by PubMed: 18715872 DOI: 10.1074/jbc.M801126200 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation