2J7Q

Crystal structure of the ubiquitin-specific protease encoded by murine cytomegalovirus tegument protein M48 in complex with a ubquitin-based suicide substrate

2J7Q の概要

• エントリーDOI: 10.2210/pdb2j7q/pdb
• 関連するPDBエントリー: 1C3T 1D3Z 1F9J 1FXT 1G6J 1GJZ 1NBF 1OGW 1Q5W 1S1Q 1SIF 1TBE 1UBI 1UBQ 1XD3 1XQQ 1YX5 1YX6 1ZGU 2AYO 2BGF 2FCM 2FCN 2FCQ 2FCS 2FUH 2G45 2GBK 2GBM 2GBN
• 分子名称: MCMV TEGUMENT PROTEIN M48 ENCODED UBIQUITIN- SPECIFIC PROTEASE, M48USP, UBIQUITIN, MAGNESIUM ION, ... (8 entities in total)
• 機能のキーワード: herpesviridae, nuclear protein, covalent enzyme-ligand complex, deubiquitinating enzyme, hydrolase, papain-like fold, cysteine protease
• 由来する生物種: MURINE CYTOMEGALOVIRUS; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 68996.69

構造登録者

Schlieker, C.,Weihofen, W.A.,Frijns, E.,Kattenhorn, L.M.,Gaudet, R.,Ploegh, H.L. (登録日: 2006-10-16, 公開日: 2007-03-20, 最終更新日: 2023-11-15)

• 主引用文献: Schlieker, C.,Weihofen, W.A.,Frijns, E.,Kattenhorn, L.M.,Gaudet, R.,Ploegh, H.L.; Structure of a Herpesvirus-Encoded Cysteine Protease Reveals a Unique Class of Deubiquitinating Enzymes; Mol.Cell, 25:677-, 2007; PubMed: 17349955; DOI: 10.1016/J.MOLCEL.2007.01.033

実験手法

X-RAY DIFFRACTION (1.8 Å)