2I9G

DNA Polymerase Beta with a Benzo[c]phenanthrene diol epoxide adducted guanine base

Summary for 2I9G

• Entry DOI: 10.2210/pdb2i9g/pdb
• Descriptor: 5'-D(P*GP*TP*CP*GP*G)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', ... (8 entities in total)
• Functional Keywords: mutagenesis, base excision repair, nucleotidyl transferase, dna adduct, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P06746
• Total number of polymer chains: 4
• Total formula weight: 48089.07

Authors

Batra, V.K.,Wilson, S.H.,Beard, W.A.,Pedersen, L.C. (deposition date: 2006-09-05, release date: 2006-10-24, Last modification date: 2023-08-30)

• Primary citation: Batra, V.K.,Shock, D.D.,Prasad, R.,Beard, W.A.,Hou, E.W.,Pedersen, L.C.,Sayer, J.M.,Yagi, H.,Kumar, S.,Jerina, D.M.,Wilson, S.H.; Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic features.; Proc.Natl.Acad.Sci.Usa, 103:17231-17236, 2006; PubMed: 17079493; DOI: 10.1073/pnas.0605069103

Experimental method

X-RAY DIFFRACTION (2.1 Å)