2HTU

N8 neuraminidase in complex with peramivir

Summary for 2HTU

Entry DOI	10.2210/pdb2htu/pdb
Related	2HT5 2HT7 2HT8 2HTQ 2HTR 2HTV 2HTW 2HTY 2HU0 2HU4
Descriptor	Neuraminidase, 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID (2 entities in total)
Functional Keywords	n8, neuraminidase, peramivir, hydrolase
Biological source	Influenza A virus
Cellular location	Virion membrane (By similarity): Q07599
Total number of polymer chains	1
Total formula weight	43485.93
Authors	Russell, R.J.,Haire, L.F.,Stevens, D.J.,Collins, P.J.,Lin, Y.P.,Blackburn, G.M.,Hay, A.J.,Gamblin, S.J.,Skehel, J.J. (deposition date: 2006-07-26, release date: 2006-09-05, Last modification date: 2011-07-13)
Primary citation	Russell, R.J.,Haire, L.F.,Stevens, D.J.,Collins, P.J.,Lin, Y.P.,Blackburn, G.M.,Hay, A.J.,Gamblin, S.J.,Skehel, J.J. The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature, 443:45-49, 2006 Cited by PubMed: 16915235 DOI: 10.1038/nature05114 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation