2HR7
Insulin receptor (domains 1-3)
Summary for 2HR7
Entry DOI | 10.2210/pdb2hr7/pdb |
Descriptor | Insulin receptor, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, GLYCEROL, ... (12 entities in total) |
Functional Keywords | hormone receptor, leucine rich repeat, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 122958.43 |
Authors | Garrett, T.P.J.,Ward, C.W. (deposition date: 2006-07-19, release date: 2006-08-15, Last modification date: 2023-08-30) |
Primary citation | Lou, M.,Garrett, T.P.,McKern, N.M.,Hoyne, P.A.,Epa, V.C.,Bentley, J.D.,Lovrecz, G.O.,Cosgrove, L.J.,Frenkel, M.J.,Ward, C.W. The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity. Proc.Natl.Acad.Sci.Usa, 103:12429-12434, 2006 Cited by PubMed: 16894147DOI: 10.1073/pnas.0605395103 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.32 Å) |
Structure validation
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