3E47

Crystal Structure of the Yeast 20S Proteasome in Complex with Homobelactosin C

Replaces:  2FNY

Summary for 3E47

• Entry DOI: 10.2210/pdb3e47/pdb
• Related: 1ryp
• Descriptor: Proteasome component Y7, Proteasome component C11, Proteasome component PRE2, ... (16 entities in total)
• Functional Keywords: proteasome, ubiquitin, protein degradation, inhibitor, immunology, cytoplasm, hydrolase, nucleus, phosphoprotein, protease, threonine protease, ubl conjugation, zymogen
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Cellular location: Cytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451
• Total number of polymer chains: 28
• Total formula weight: 705401.64

Authors

Groll, M.,Larionov, O.V.,de Meijere, A. (deposition date: 2008-08-10, release date: 2008-09-02, Last modification date: 2023-11-01)

• Primary citation: Groll, M.,Larionov, O.V.,Huber, R.,de Meijere, A.; Inhibitor-binding mode of homobelactosin C to proteasomes: new insights into class I MHC ligand generation; Proc.Natl.Acad.Sci.Usa, 103:4576-4579, 2006; PubMed: 16537370; DOI: 10.1073/pnas.0600647103

Experimental method

X-RAY DIFFRACTION (3 Å)