2F8O

A Native to Amyloidogenic Transition Regulated by a Backbone Trigger

Summary for 2F8O

• Entry DOI: 10.2210/pdb2f8o/pdb
• Descriptor: Beta-2-microglobulin (2 entities in total)
• Functional Keywords: beta-sandwich, amyloid, class-1 mhc, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Secreted . Note=(Microbial infection) In the presence of M: P61769
• Total number of polymer chains: 2
• Total formula weight: 23706.64

Authors

Eakin, C.M.,Berman, A.J.,Miranker, A.D. (deposition date: 2005-12-02, release date: 2006-02-21, Last modification date: 2023-08-30)

• Primary citation: Eakin, C.M.,Berman, A.J.,Miranker, A.D.; A native to amyloidogenic transition regulated by a backbone trigger.; Nat.Struct.Mol.Biol., 13:202-208, 2006; PubMed: 16491088; DOI: 10.1038/nsmb1068

Experimental method

X-RAY DIFFRACTION (1.7 Å)