2F74

Murine MHC class I H-2Db in complex with human b2-microglobulin and LCMV-derived immunodminant peptide gp33

Summary for 2F74

• Entry DOI: 10.2210/pdb2f74/pdb
• Related: 1N5A 1S7U
• Descriptor: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, NONAMERIC PEPTIDE, GP33, DERIVED FROM LYMPHOCYTIC CHORIOMENINGITIS VIRUS, ... (4 entities in total)
• Functional Keywords: murine mhc, lcmv, receptor binding, beta2-microglobulin, immune system
• Biological source: Mus musculus (house mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01899; Secreted . Note=(Microbial infection) In the presence of M: P61769
• Total number of polymer chains: 6
• Total formula weight: 90024.58

Authors

Achour, A.,Michaelsson, J.,Harris, R.A.,Ljunggren, H.G.,Karre, K.,Schneider, G.,Sandalova, T. (deposition date: 2005-11-30, release date: 2006-02-14, Last modification date: 2023-08-23)

• Primary citation: Achour, A.,Harris, R.A.,Ljunggren, H.G.,Schneider, G.,Sandalova, T.; Structural Basis of the Differential Stability and Receptor Specificity of H-2D(b) in Complex with Murine versus Human beta(2)-Microglobulin.; J.Mol.Biol., 356:382-396, 2006; PubMed: 16375919; DOI: 10.1016/j.jmb.2005.11.068

Experimental method

X-RAY DIFFRACTION (2.7 Å)