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2CGX

Identification of chemically diverse Chk1 inhibitors by receptor- based virtual screening

2CGX の概要
エントリーDOI10.2210/pdb2cgx/pdb
関連するPDBエントリー1IA8 1NVQ 1NVR 1NVS 2BR1 2BRB 2BRG 2BRH 2BRM 2BRN 2BRO 2C3J 2C3K 2C3L 2CGU 2CGV 2CGW
分子名称SERINE/THREONINE-PROTEIN KINASE CHK1, 2-[(6-AMINO-7H-PURIN-8-YL)THIO]ACETAMIDE (3 entities in total)
機能のキーワードtransferase, docking, drug design, oncology, virtual screening, atp- binding, cell cycle, dna damage, dna repair, kinase, nuclear protein, nucleotide-binding, phosphorylation, polymorphism, serine/threonine-protein kinase, ubl conjugation
由来する生物種HOMO SAPIENS (HUMAN)
タンパク質・核酸の鎖数1
化学式量合計34372.39
構造登録者
Foloppe, N.,Fisher, L.M.,Howes, R.,Potter, A.,Robertson, A.G.S.,Surgenor, A.E. (登録日: 2006-03-09, 公開日: 2006-04-05, 最終更新日: 2023-12-13)
主引用文献Foloppe, N.,Fisher, L.M.,Howes, R.,Potter, A.,Robertson, A.G.S.,Surgenor, A.E.
Identification of Chemically Diverse Chk1 Inhibitors by Receptor-Based Virtual Screening.
Bioorg.Med.Chem., 14:4792-, 2006
Cited by
PubMed: 16574416
DOI: 10.1016/J.BMC.2006.03.021
主引用文献が同じPDBエントリー
実験手法
X-RAY DIFFRACTION (2.2 Å)
構造検証レポート
Validation report summary of 2cgx
検証レポート(詳細版)ダウンロードをダウンロード

217705

件を2024-03-27に公開中

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