2CET

Beta-glucosidase from Thermotoga maritima in complex with phenethyl- substituted glucoimidazole

2CET の概要

• エントリーDOI: 10.2210/pdb2cet/pdb
• 関連するPDBエントリー: 1OD0 1OIF 1OIM 1OIN 1UZ1 1W3J 2CBU 2CBV 2CES
• 分子名称: BETA-GLUCOSIDASE A, ACETATE ION, (5R,6R,7S,8S)-5-(HYDROXYMETHYL)-2-(2-PHENYLETHYL)-1,5,6,7,8,8A-HEXAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, ... (5 entities in total)
• 機能のキーワード: glycoside hydrolase, inhibitor, transition state mimic, family 1, phenethyl-substituted glucoimidazole, hydrolase
• 由来する生物種: THERMOTOGA MARITIMA
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 108591.12

構造登録者

Gloster, T.M.,Roberts, S.,Vasella, A.,Davies, G.J. (登録日: 2006-02-10, 公開日: 2006-09-27, 最終更新日: 2023-12-13)

• 主引用文献: Gloster, T.M.,Roberts, S.,Perugino, G.,Rossi, M.,Moracci, M.,Panday, N.,Terinek, M.,Vasella, A.,Davies, G.J.; Structural, Kinetic, and Thermodynamic Analysis of Glucoimidazole-Derived Glycosidase Inhibitors.; Biochemistry, 45:11879-, 2006; PubMed: 17002288; DOI: 10.1021/BI060973X

実験手法

X-RAY DIFFRACTION (1.97 Å)