2CBL

N-TERMINAL DOMAIN OF CBL IN COMPLEX WITH ITS BINDING SITE ON ZAP-70

2CBL の概要

• エントリーDOI: 10.2210/pdb2cbl/pdb
• 分子名称: PROTO-ONCOGENE CBL, ZAP-70, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: proto-oncogene, signal transduction, phosphotyrosine binding, sh2, complex (proto-oncogene-peptide), complex (proto-oncogene-peptide) complex, complex (proto-oncogene/peptide)
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P22681
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36814.31

構造登録者

Meng, W.,Sawasdikosol, S.,Burakoff, S.J.,Eck, M.J. (登録日: 1998-08-28, 公開日: 1999-05-18, 最終更新日: 2024-04-03)

• 主引用文献: Meng, W.,Sawasdikosol, S.,Burakoff, S.J.,Eck, M.J.; Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase.; Nature, 398:84-90, 1999; PubMed: 10078535; DOI: 10.1038/18050

実験手法

X-RAY DIFFRACTION (2.1 Å)