2C7U

Conflicting selective forces affect CD8 T-cell receptor contact sites in an HLA-A2 immunodominant HIV epitope.

Summary for 2C7U

• Entry DOI: 10.2210/pdb2c7u/pdb
• Related: 1A1M 1A1N 1A1O 1A6Z 1A9B 1A9E 1AGB 1AGC 1AGD 1AGE 1AGF 1AKJ 1AO7 1AQD 1B0G 1B0R 1BD2 1C16 1CE6 1CG9 1DE4 1DUY 1DUZ 1E27 1E28 1EEY 1EEZ 1EFX 1EXU 1GZP 1GZQ 1HHG 1HHH 1HHI 1HHJ 1HHK 1HLA 1HSA 1HSB 1I1F 1I1Y 1I4F 1I7R 1I7T 1I7U 1IM3 1IM9 1JF1 1JHT 1JNJ 1K5N 1KPR 1KTL 1LDS 1LP9 1M05 1M6O 1MHE 1MI5 1N2R 1OF2 1OGA 1OGT 1ONQ 1P7Q 1PY4 1Q94 1QEW 1QR1 1QRN 1QSE 1QSF 1QVO 1R3H 1S9W 1S9X 1S9Y 1SYS 1SYV 1T1W 1T1X 1T1Y 1T1Z 1T20 1T21 1T22 1TMC 1TVB 1TVH 1UQS 1UR7 1UXS 1UXW 1VGK 1W0V 1W0W 1W72 1X7Q 1XH3 1XR8 1XR9 1XZ0 1YDP 1YPZ 1ZS8 1ZSD 1ZT4 2AK4 2AV1 2AV7 2BNQ 2BNR 2BSR 2BSS 2BST 2BSU 2BSV 2BVQ 2CLR 3HLA
• Descriptor: HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2-MICROGLOBULIN, GAG PROTEIN, ... (4 entities in total)
• Functional Keywords: glycoprotein-peptide complex, mhc, tcr, hla-a2, hiv, glycoprotein, immune response, mhc i, transmembrane, immunoglobulin domain, pyrrolidone carboxylic acid, aids, glycoprotein/peptide
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769
• Total number of polymer chains: 6
• Total formula weight: 89615.65

Authors

Iversen, A.K.,Stewart-Jones, G.,Learn, G.H.,Christie, N.,Sylvester-Hviid, C.,Armitage, A.E.,Kaul, R.,Beattie, T.,Lee, J.K.,Li, Y.,Chotiyarnwong, P.,Dong, T.,Xu, X.,Luscher, M.A.,MacDonald, K.,Ullum, H.,Klarlund-Pedersen, B.,Skinhoj, P.,Fugger, J.L.,Buus, S.,Mullins, J.I.,Jones, E.Y.,van der Merwe, P.A.,McMichael, A.J. (deposition date: 2005-11-29, release date: 2006-03-08, Last modification date: 2011-07-13)

• Primary citation: Iversen, A.K.,Stewart-Jones, G.,Learn, G.H.,Christie, N.,Sylvester-Hviid, C.,Armitage, A.E.,Kaul, R.,Beattie, T.,Lee, J.K.,Li, Y.,Chotiyarnwong, P.,Dong, T.,Xu, X.,Luscher, M.A.,Macdonald, K.,Ullum, H.,Klarlund-Pedersen, B.,Skinhoj, P.,Fugger, L.,Buus, S.,Mullins, J.I.,Jones, E.Y.,Van Der Merwe, P.A.,Mcmichael, A.J.; Conflicting Selective Forces Affect T Cell Receptor Contacts in an Immunodominant Human Immunodeficiency Virus Epitope.; Nat.Immunol., 7:179-, 2006; PubMed: 16388312; DOI: 10.1038/NI1298

Experimental method

X-RAY DIFFRACTION (2.38 Å)