2BBA

Crystal Structure and Thermodynamic Characterization of the EphB4 Receptor in Complex with an ephrin-B2 Antagonist Peptide Reveals the Determinants for Receptor Specificity.

Summary for 2BBA

Entry DOI	10.2210/pdb2bba/pdb
Descriptor	Ephrin type-B receptor 4, Agonist peptide, SULFATE ION, ... (4 entities in total)
Functional Keywords	ephb4, tumorigenesis, angiogenesis, peptide mimetics, signaling protein, structural genomics, psi-2, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P54760
Total number of polymer chains	2
Total formula weight	22987.99
Authors	Chrencik, J.E.,Kuhn, P.,Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) (deposition date: 2005-10-17, release date: 2006-07-18, Last modification date: 2023-08-23)
Primary citation	Chrencik, J.E.,Brooun, A.,Recht, M.I.,Kraus, M.L.,Koolpe, M.,Kolatkar, A.R.,Bruce, R.H.,Martiny-Baron, G.,Widmer, H.,Pasquale, E.B.,Kuhn, P. Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity. Structure, 14:321-330, 2006 Cited by PubMed: 16472751 DOI: 10.1016/j.str.2005.11.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation