2B2V

Crystal structure analysis of human CHD1 chromodomains 1 and 2 bound to histone H3 resi 1-15 MeK4

Summary for 2B2V

• Entry DOI: 10.2210/pdb2b2v/pdb
• Related: 1kna 1kne 1pdq 1q3l 2b2t 2b2u 2b2w 2b2y
• Descriptor: Chromodomain-helicase-DNA-binding protein 1, Histone H3, ... (4 entities in total)
• Functional Keywords: chd, chromodomain, three stranded antiparallel beta sheet, alpha helix linker, histone h3, monomethyllysine, peptide binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : O14646 O14646 P68431
• Total number of polymer chains: 4
• Total formula weight: 59729.81

Authors

Flanagan IV, J.F.,Mi, L.-Z.,Chruszcz, M.,Cymborowski, M.,Clines, K.L.,Kim, Y.,Minor, W.,Rastinejad, F.,Khorasanizadeh, S. (deposition date: 2005-09-19, release date: 2005-12-27, Last modification date: 2024-04-03)

• Primary citation: Flanagan, J.F.,Mi, L.Z.,Chruszcz, M.,Cymborowski, M.,Clines, K.L.,Kim, Y.,Minor, W.,Rastinejad, F.,Khorasanizadeh, S.; Double chromodomains cooperate to recognize the methylated histone H3 tail.; Nature, 438:1181-1185, 2005; PubMed: 16372014; DOI: 10.1038/nature04290

Experimental method

X-RAY DIFFRACTION (2.65 Å)